The disease that causes AIDS is considered to be incurable HIV and currently some people have been able to recover completely with a specific treatment.
But in 1992, a 66-year-old HIV-positive woman became the first person in the world to defeat the autoimmune disease without medication or a bone marrow transplant.
This is a unique case of its kind and researchers have been researching Lorraine Welenberg from California for a long time.
She was one of 0.5% of HIV patients whose immune systems function naturally like antiviral drugs.
That is, the immune system itself weakened this incurable virus so much that it became extinct.
In this regard, a new research paper has now been published in the journal Nature, according to which Lorraine is the first person in this unique group of HIV patients to be able to completely eradicate the virus from her body.
The researchers examined 1.5 billion cells in their blood, intestines and stomach, all of which turned out to be HIV-positive.
This is an unprecedented case that has led to the expectation that this could happen to millions of HIV patients who use antiviral drugs to control the virus.
The researchers said that this suggests that the treatment itself treats the logo, which is against the idea that drugs can reduce the spread or severity of the virus, but complete recovery is not possible.
Along with Lorraine, the Reagan Institute was researching 64 people like her who have the ability to control their HIV without medication.
With the exception of Lorraine, the other 63 people naturally controlled their HIV in such a way that they could not make copies.
In addition to being a unique source of HIV control, Lorraine is also known for her contributions to research reports and is a leading figure in the field of HIV / AIDS research.
Before Lorraine, 2 people have been declared fully HIV positive.
Earlier in 2007, a patient named Timothy Brown was declared healthy after undergoing a bone marrow transplant to treat leukemia and he is still safe from this disease after a decade.
Similarly, another patient, Ed Casteljo, made headlines last year when he was declared HIV-free through stem cells from a genetically resistant donor.
This year, a man from Brazil was named the first person in the world to be cured of HIV by experimental medicine alone.
The 34-year-old was diagnosed with HIV in 2012 and used AVR for a year and is now set to become the first person to come close to overcoming an incurable disease.
Along with this person, 4 other people were also made part of the experimental treatment but only he was able to recover.
The researchers said more analysis was needed.
The Brazilian is one of only three people in the world to have survived the disease.
The patient underwent conventional AVR therapy for the first 2 months and was then made part of a clinical trial in which he was treated with ART as well as the HIV drugs dolutegravir and marivoc, as well as a type of vitamin B Nicotinamide was also given.
Nicotinamide plays a role in fighting the virus in infected cells, forcing them to destroy them and stimulating the immune system.
The patient underwent one year of treatment and was removed from the trial in March 2019.
Since then it has been tested every 3 weeks and no viral load or antibodies have been detected even after one year.
Dr. Ricardo Diaz of the University of S ساo Paulo, who led the study, said he had tried to awaken the virus and boost the immune system to eliminate the hidden virus at once.
"We do not examine the whole body, but in the best results we have not been able to detect the affected cells. I think this is very encouraging. This patient has probably recovered, but his final decision will take some time," he said. It will happen later.
If this new experimental treatment works in other patients, it will be a huge breakthrough.
At present, HIV patients have to use medication to suppress the viral load for life.
